This article examines whether the effect of interethnic encounters on natives’ attitudes towards immigration varies with the Big Five personality trait openness to experience. We hypothesize that individuals who score high on openness, and who therefore are more appreciative of and responsive to new experiences, react more positively/less negatively to interethnic encounters. We test this conjecture on two surveys collected in Denmark and Canada. In line with our expectations, the analyses suggest that openness positively moderates the effect of interethnic encounters on immigration attitudes: compared to those with lower levels of openness, more open individuals express more pro-immigration attitudes when experiencing both personal interethnic contact and self-reported exposure to ethnic diversity in the neighbourhood.