Transforming growth factor-β activation in cell-free extracellular matrix preparations: Commentary

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Transforming growth factor-β activation in cell-free extracellular matrix preparations : Commentary. / Couchman, John R.

In: Folia Histochemica et Cytobiologica, Vol. 57, No. 4, 2019, p. 157-158.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Couchman, JR 2019, 'Transforming growth factor-β activation in cell-free extracellular matrix preparations: Commentary', Folia Histochemica et Cytobiologica, vol. 57, no. 4, pp. 157-158. https://doi.org/10.5603/FHC.a2019.0017

APA

Couchman, J. R. (2019). Transforming growth factor-β activation in cell-free extracellular matrix preparations: Commentary. Folia Histochemica et Cytobiologica, 57(4), 157-158. https://doi.org/10.5603/FHC.a2019.0017

Vancouver

Couchman JR. Transforming growth factor-β activation in cell-free extracellular matrix preparations: Commentary. Folia Histochemica et Cytobiologica. 2019;57(4):157-158. https://doi.org/10.5603/FHC.a2019.0017

Author

Couchman, John R. / Transforming growth factor-β activation in cell-free extracellular matrix preparations : Commentary. In: Folia Histochemica et Cytobiologica. 2019 ; Vol. 57, No. 4. pp. 157-158.

Bibtex

@article{d8eaa9c77e6445f6b2f4591d784432bb,
title = "Transforming growth factor-β activation in cell-free extracellular matrix preparations: Commentary",
abstract = "Transforming growth factor-β (TGF-β) is an important regulator of many cellular and immunological functions. It is often deposited in extracellular matrices in a latent form. This commentary is to draw attention to the likelihood that preparing cell-free matrices from tissue cultures by high pH buffers, such as ammonium hydroxide, can activate the TGF-β. Therefore, cells subsequently seeded onto such matrices may respond to the presence of active TGF-β in addition to interactions with macromolecular extracellular matrix components.",
keywords = "Faculty of Health and Medical Sciences",
author = "Couchman, {John R}",
year = "2019",
doi = "10.5603/FHC.a2019.0017",
language = "English",
volume = "57",
pages = "157--158",
journal = "Folia Histochemica et Cytobiologica",
issn = "0239-8508",
publisher = "WydawnictwoVia Medica",
number = "4",

}

RIS

TY - JOUR

T1 - Transforming growth factor-β activation in cell-free extracellular matrix preparations

T2 - Commentary

AU - Couchman, John R

PY - 2019

Y1 - 2019

N2 - Transforming growth factor-β (TGF-β) is an important regulator of many cellular and immunological functions. It is often deposited in extracellular matrices in a latent form. This commentary is to draw attention to the likelihood that preparing cell-free matrices from tissue cultures by high pH buffers, such as ammonium hydroxide, can activate the TGF-β. Therefore, cells subsequently seeded onto such matrices may respond to the presence of active TGF-β in addition to interactions with macromolecular extracellular matrix components.

AB - Transforming growth factor-β (TGF-β) is an important regulator of many cellular and immunological functions. It is often deposited in extracellular matrices in a latent form. This commentary is to draw attention to the likelihood that preparing cell-free matrices from tissue cultures by high pH buffers, such as ammonium hydroxide, can activate the TGF-β. Therefore, cells subsequently seeded onto such matrices may respond to the presence of active TGF-β in addition to interactions with macromolecular extracellular matrix components.

KW - Faculty of Health and Medical Sciences

U2 - 10.5603/FHC.a2019.0017

DO - 10.5603/FHC.a2019.0017

M3 - Journal article

C2 - 31743418

VL - 57

SP - 157

EP - 158

JO - Folia Histochemica et Cytobiologica

JF - Folia Histochemica et Cytobiologica

SN - 0239-8508

IS - 4

ER -

ID: 231600560